Peer-Reviewed
(ISG authors in bold type)
2022
Zheng B, Lu Q, Zheng F. “Gene-by-Peer-Environment Interaction Effects on Cigarette, Alcohol, and Marijuana Use Among US High School Students of European Ancestry.” Social Science & Medicine. 2022 Sep; 309: 115249.
Okbay A, Wu Y, Wang N, … Koellinger PD, et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics. 2022 Mar.
Wu Y, Furuya S, Lu Q, Wang Z, Nobles JE, Fletcher JM, Lu Q. “GWAS on birth year infant mortality rates provides evidence of recent natural selection.” PNAS. 2022 Mar; 119 (12) e2117312119.
Daviet R, Aydogan G, Jagannathan K, Spilka N, Koellinger PD, et al. “Associations between alcohol consumption and gray and white matter volumes in the UK Biobank.” Nature Communications. 2022 Mar; 13, 1175.
Fiorito G, … Zhang Y, . . . Schmitz LL, et al. “The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis.” The Journals of Gerontology: Series A, 2022 Feb; glac041.
Karlsson Linnér R, Koellinger PD. “Genetic risk scores in life insurance underwriting.” Journal of Health Economics. 2022; 81, 102556.
2021
Furuyu S, Fletcher JM, Zhao Z, Sun Z, Lu Q. “Detecting genetic heterogeneities in response to trauma: The case of 9/11.” SSM–Mental Health. 2021 Dec; 2, 100044.
de Vlaming R, Slob EAW, Jansen PR, Dagher A, Koellinger PD, Groenen PJF, Rietveld CA. “Multivariate analysis reveals shared genetic architecture of brain morphology and human behavior.” Communications Biology. 2021 Oct; 4, 1180.
–BioRxiv
He Q, Li JJ. “A Gene-Environment Interaction Study of Polygenic Scores and Maltreatment on Childhood ADHD.” Research on Child and Adolescent Psychopathology. 2021 Oct.
Zhang Y, Lu Q, Ye Y, Huang K, Liu W, Wu Y, Zhong X, Li B, Yu Z, Travers B, Werling D, Li J, Zhao H. “SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits.” Genome Biology. 2021 Sep; 22, 262.
Zhao Z, Yi Y, Song J, Wu Y, Zhong X, Lin Y, Hohman T, Fletcher J, Lu Q. “PUMAS: fine-tuning polygenic risk scores with GWAS summary statistics.” Genome Biology. 2021 Sep; 22, 257.
Karlsson Linnér R, Mallard TT, Barr PB, . . . Koellinger PD. “Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.” Nature Neuroscience. 2021 Aug.
Becker J, Burik CAP, . . . Koellinger PD, . . . Cesarini D, Benjamin DJ, Turley P, Okbay A. “Resource profile and user guide of the Polygenic Index Repository.” Nature Human Behaviour, 2021 Jul.
–BioRxiv
Fletcher J, Topping M, Zheng F, Lu Q. “The effects of education on cognition in older age: evidence from genotyped siblings.” Social Science & Medicine. 2021 Jul; 280: 114044.
Schmitz L, Zhao W, Ratliff S, Goodwin J, Miao J, Lu Q, Guo X, Taylor K, Ding J, Liu Y, Levine M, Smith J. “The socioeconomic gradient in epigenetic aging clocks: evidence from the Multi-ethnic Study of Atherosclerosis and the Health and Retirement Study.” Epigenetics. 2021 Jul.
Wu Y, Zhong X, Lin Y, Zhao Z, Chen J, Zheng B, Li J, Fletcher J, Lu Q. “Estimating genetic nurture with summary statistics of multi-generational genome-wide association studies.” Proceedings of the National Academy of Sciences. 2021 Jun; 118(25): e2023184118.
Guo H, Li J, Lu Q, Hou L. “Detecting local genetic correlations with scan statistics.” Nature Communications. 2021 Apr; 12: 2033.
Gard AM, Ware EB, Hyde LW, Schmitz LL, Faul J, Mitchell CM. “Phenotypic and genetic markers of psychopathology in a population-based sample of older adults.” Translational Psychiatry. 2021 Apr; 11:239
Schmitz L, Goodwin J, Miao J, Lu Q, Conley D. “The impact of late-career job loss and genetic risk on body mass index: evidence from variance polygenic scores.” Scientific Reports. 2021 Apr; 11: 7647.
Aydogan G, Daviet R, Karlsson Linnér R, Kranzler HR, Wetherhill RR, Ruff CC, Koellinger PD, Nave G. “Genetic underpinnings of risky behavior relate to altered neuroanatomy.” Nature Human Behaviour, 2021 Jan.
–BioRxiv
Li JJ, He Q. “Polygenic Scores for ADHD: A Meta-Analysis.” Research on Child and Adolescent Psychopathology. 2021 Jan.
Fletcher JM, Lu Q. “Health Policy and Genetic Endowments: Understanding Sources of Response to Minimum Legal Drinking Age Laws.” Health Economics. 2021 Jan; 30(1): 194-203.
2020
Spreng RN, Dimas E, Mwilambwe-Tshilobo L, Dagher A, Koellinger P, et al. “The default network of the human brain is associated with perceived social isolation.” Nature Communications. 2020 Dec; 11.
Liu Z, Leung D, Thrush K, Zhao W, Ratliff S, Tanaka T, Schmitz LL, Smith JA, Ferrucci L, Levine ME. “Underlying features of epigenetic aging clocks in vivo and in vitro.” Aging Cell. 2020 Sep.
Greenberg J, Hilton EC, Li JJ, Lu Q, Mailick MR. “The impact of parenting a child with serious mental illness: Accounting for the parent’s genetic vulnerability to mental illness.” Journal of Family Psychology. 2020 Jul.
Harvey PD, Sun N, Lu Q, et al. “Genome‐wide association study of cognitive performance in US veterans with schizophrenia or bipolar disorder.” American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2020 Apr; 183(3): 181-194.
Domingue B, Fletcher JM. “Separating Measured Genetic and Environmental Effects: Evidence Linking Parental Genotype and Adopted Child Outcomes.” Behavior Genetics. 2020 Apr; 50: 301-309.
Hatchell KE, Lu Q, Mares JA, Michos ED, Wood AC, Engelman CD. “Multi‐ethnic analysis shows genetic risk and environmental predictors interact to influence 25 (OH) D concentration and optimal vitamin D intake.” Genetic Epidemiology. 2020 Mar; 44(2): 208-217.
2019
Li JJ, Hilton EC, Lu Q, Hong J, Greenberg JS, Mailick MR. “Validating psychosocial pathways of risk between neuroticism and late life depression using a polygenic score approach.” Journal of Abnormal Psychology. 2019. 128(3): 200–211.
Li, JJ. “The positive end of the polygenic score distribution for ADHD: a low risk or a protective factor?” Psychological Medicine. 2019 Oct; 1-10.
Darst BF, Lu Q, Johnson SC, Engelman CD. “Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer’s risk factors among 1,111 cohort participants.” Genetic Epidemiology. 2019 Sep; 43(6): 657-674.
Gelernter J, Sun N, Polimanti R, Pietrzak, Lu Q, et al. “Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci.” Biological Psychiatry. 2019 Sep; 86(5), 365-376.
Hatchell KE, Lu Q, Hebbring SJ, Engelman CD, et al. “Ancestry-specific polygenic scores and SNP heritability of 25(OH)D in African- and European-ancestry populations.” Human Genetics. 2019 Jul; 138: 1155-1169.
Gelernter J, Sun N, Polimanti R, Pietrzak, Lu Q, et al. “Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in> 165,000 US veterans.” Nature Neuroscience. 2019 Jul; 22(9): 1394-1401.
Lu Q, Zhao H. “Improving Genetic Association Analysis through Integration of Functional Annotations of the Human Genome.” In: Balding D, Moltke I, Marioni J, eds. Handbook of Statistical Genomics. 4th ed. 2019 Jul; 679-30.
Schmitz LL, Gard AM, Ware EB. “Examining sex differences in pleiotropic effects for depression and smoking using polygenic and gene‐region aggregation techniques.” American Journal of Medical Genetics. 2019 Jun; 180(6): 448-468.
Li B, Lu Q, Zhao H. “An evaluation of noncoding genome annotation tools through enrichment analysis of 15 genome-wide association studies.” Briefings in Bioinformatics. 2019 May; 20(3): 995-1003.
Li JJ. “Assessing phenotypic and polygenic models of ADHD to identify mechanisms of risk for longitudinal trajectories of externalizing behaviors.” Journal of Child Psychology and Psychiatry. 2019 May. 60 (11): 1191-1199.
Hu B, Shen N, Li JJ, Kang H, Hong J, Fletcher JM, Greenberg JS, Mailick MR, Lu Q. “Genome-wide association study reveals sex-specific genetic architecture of facial attractiveness.” PLOS Genetics. 2019 Apr; 15(4): e1007973.
Darst BF, Koscik RL, Hogan KJ, Johnson SC, Engelman CD. “Longitudinal plasma metabolomics of aging and sex” Aging. 2019 Feb; 11(4): 1262-1282.
Koscik RL, Norton DL, Allison SL, Engelman CD, et al. “Characterizing the Effects of Sex, APOE ɛ4, and Literacy on Mid-life Cognitive Trajectories: Application of Information-Theoretic Model Averaging and Multi-model Inference Techniques to the Wisconsin Registry for Alzheimer’s Prevention Study.” Journal of the International Neuropsychological Society. 2019 Feb; 25(2): 119-133.
Hu Y, Li M, Lu Q, et al. “A statistical framework for cross-tissue transcriptome-wide association analysis.” Nature Genetics. 2019 Feb; 51(3): 568-576.